Making medication unique through personalised dosing

Wednesday 30 September 2015
14:30-17:30
B5*     Session accredited under ACPE, UAN: 0579-0000-15-008-L04-P (3.0 contact hours)

Organised by the FIP SIG on Formulation Design and Pharmaceutical Technology, the FIP Hospital Pharmacy Section and the FIP SIG on Translational Research and Individualised Medicines

Introduction

Personalised medicines are predicted to increase safety and efficacy of drugs due to special consideration of the unique genetic make-up of patient sub-populations. Conventional prescription medicine today, however, applies a "one size fits all" approach, which does not offer sufficient flexibility for individualised dosing. To pave the way towards future healthcare systems with integrated personalised medicines, innovative drug formulation concepts and novel devices for dispensing are needed. Adequate dosing systems for individualised medicines are particularly critical high potency drugs and vulnerable patient populations such as paediatric and geriatric patients. This session highlights the therapeutic benefits of individualised dosing and summarises current opportunities for practitioners to tailor dose regimens to the needs of special patient populations. In addition, new drug formulation concepts will be presented that are predicted to allow practitioners increased dosing flexibility for more effective implementation of personalised medicine strategies.

Learning objectives

Knowledge-based session

At the conclusion of this session, participants will be able to:

  1. Explain flexible dosing opportunities for specialised patient populations using conventional and novel formulations.
  2. Analyse the concept of monolithic solid dosage forms in personalised medicine.
  3. Describe the development of pharmacy computer system clinical decision support tools that address personalised doses for specific medicines.  
  4. List examples of opportunities for pharmacists to maximise therapeutic outcomes through personalised medicine.

Chairs: Marianne Ivey (University of Cincinnati, USA) and Tetsuya Ozeki (Nagoya City University, Japan)

Programme

14:30 1) Defining the role of a pharmacist in personalised medicine
Hitoshi Sasaki (Nagasaki University Hospital, Japan)

15:10 2) Building personalised dosing into clinical decision support
Kelly Caudle (St. Jude Children's Research Hospital, USA)

15:50 Break

16:10 3) Individual oral therapy using the novel solid dosage pen
Joerg Breitkreutz (Heinrich Heine University, Germany) 

16:50 4) Printing technologies that potentially personalise doses and dosage forms
Niklas Sandler (Åbo Akademi University, Finland)